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Before & After: Setting Realistic Tirzepatide Expectations The ideal candidate for tirzepatide therapy is typically someone with a BMI of 30 or higher, or a BMI of 27 or higher accompanied by weight-related comorbidities such as hypertension, high cholesterol, insulin resistance, or type 2 diabetes

The side effects we occasionally see in clinic are mild and typically transient

The combination shows approximately 15-18% weight loss, falling between semaglutide alone and tirzepatide

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