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Cross-species dose conversion requires extensive pharmacokinetic and pharmacodynamic studies beyond simple body weight or surface area calculations

UVA-photoactivated riboflavin effect on isolated vaginal tissues derived from pelvic organ prolapse cases

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Novakovic MM, Korshunov KS, Grant RA, Martin ME, Valencia HA, Budinger GRS, et al

While no mechanism suggests delayed toxicity, this cannot be completely ruled out without long-term controlled studies