While a mere 8% of patients undergoing clinical monitoring experienced improvements in their depressive symptoms, significant improvement was noted in 56% of those engaged in cognitive-behavioral therapy
Where semaglutide, a GLP-1-only agonist, produces roughly 15% body weight loss on average, tirzepatide pushes past 20%
Alternatively, those in the placebo group maintained only 49.2% of their prior weight loss, resulting in a treatment difference of around 25.5% weight reduction
that kickstarted the widespread adoption of weight-loss medications
however, further investigations are warranted
The market is expected to grow from $43,904 million in 2025 at a compound annual growth rate (CAGR) of 13%