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What the Research Says Several studies confirm that even mild dehydration may impair energy, mental performance, and physical endurance: A 2011 study found that just 1 } Explore More from This Series: The 4 Most Common Side Effects of GLP-1s And How to Manage Them Muscle Loss on GLP-1s

The SURMOUNT-1 study was a placebo-controlled 72-week trial in obese subjects that randomized 2,539 participants without diabetes into four equally large study arms with placebo or one of the three tirzepatide doses (5, 10, or 15 mg once weekly)

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In short, the relationship between IVM-induced apoptosis and autophagy involves a complex regulatory mechanism, and the specific molecular mechanism needs further study

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