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Receptor Selectivity Assays As DPDPE showed the highest efficacy results, further in vitro studies were carried out to evaluate potential activities on other incretin-related receptors, as occur with dual agonist like tirzepatide (GLP1R/GIPR), survodutide (GLP1R/GCGR) and other experimental agonists like THDBH120 (GLP1R/GIPR) and MEDI0382 and SAR425899 (GLP1R/GCGR) (Zikhai Zheng et al., 2024

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Potential indirect effects include: Improved exercise recovery Better training consistency Reduced inflammation Enhanced mobility Gastrointestinal support Greater overall wellness These factors can make it easier for someone to maintain the habits that lead to sustainable weight loss

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