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Make sure to discuss with your doctor all the side effects that you encounter during the course of medication and the gravity of fatigue that you experienced

The fumarate component may contribute to the compound's stability and bioavailability

As a consequence, a loss of lipoic acid-dependent enzymatic activity caused by defects in endogenous lipoic acid synthesis (see Deficiency) cannot be rescued by the provision of exogenous lipoic acid (5)

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