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PMID: 32554853 Research Square Preprint2020 Jun

Insulin action leads to an increase in the activity of PI3K which in turn phosphorylates membrane phospholipids generating phosphatidylinositol-3,4,5-trisphophate (PIP 3 ) from phosphatidylinositol-4,5-bisphosphate (PIP 2 )

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has received research funding from Amneal, Biogen, Neuroderm, Prevail, Roche, and UCB and is an investigator for NINDS and The Michael J Fox Foundation for Parkinsons Research

For a full breakdown of how AOD 9604 works, check out our companion article