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People with type 2 diabetes are advised to limit their junk food intake and instead focus on maintaining a healthy diet that is rich in nutrients

While dose adjustment is not generally required for mild to moderate renal or hepatic impairment, tirzepatide has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis, and is not recommended in these populations

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doi: 10.3390/cells7070084 129 KomatsuS-iWatanabeHOkaTTsugeHNiiHKatoN

References: FDA Mounjaro Approval, FDA Zepbound Approval Indications and Contraindications Approved Uses Type 2 diabetes mellitus (as an adjunct to diet and exercise) Chronic weight management in adults with BMI 30 kg/m, or 27 kg/m with at least one weight-related comorbidity Contraindications Personal or family history of medullary thyroid carcinoma (MTC) Multiple endocrine neoplasia syndrome type 2 (MEN 2) Hypersensitivity to tirzepatide or any component of the formulation Note: Tirzepatide is not indicated for use in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis

APTT, activated partial thromboplastin time