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Plateaus can occur because: your metabolism has adapted to your lower weight, youve unconsciously increased caloric intake, you need a dose adjustment, youre retaining water temporarily, or youre building muscle while losing fat (improving body composition without scale changes)

They may want to see blood work to ensure metabolic markers are responding appropriately, check your energy levels and overall wellbeing, and determine whether to continue, modify, or discontinue the split dosing approach

Safety, Side Effects, and What to Expect GLP-1 medications are generally well-tolerated, with the most common side effects being mild nausea, slight appetite reduction (the intended effect), and occasional constipation during the first few weeks

Journal of Alternative and Complementary Medicine , 17(9), 827-833

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