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Kidney Dysfunction: In chronic kidney disease (CKD) or renal failure, the bodys ability to filter and excrete B12 may be compromised, leading to accumulation in the blood 8

CaT-ME promoted hair growth in mice The color of C57BL/6 mice skin correlates with the hair follicle cycle, and the growth cycle of the hair follicle can be determined based on changes in skin color of the mice [49,50]

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however, these occurred in a closely monitored clinical setting where prompt intervention was available

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