Lavertu, G., Cote, S
Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation
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The protocol that prevents this is straightforward to describe and takes effort to execute: maintain the protein anchor, hold the training volume, transition off the medication on a planned taper rather than a sudden stop, and run a structured maintenance phase where the new body composition is held and tested at maintenance calories before any other goal is layered on