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Constipation is another driver

Our findings suggest that GLP-1RAs may offer benefits beyond their effects on weight and glucose control, particularly for cardiovascular and psychiatric outcomes in people with psoriasis, explained study lead author Professor Ralf Ludwig, dermatologist and professor and director at the Lbeck Institute of Experimental Dermatology, University of Lbeck, Germany

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In addition, the experimental conditions impacted the inhibitory half-life of the enzyme, which was 462.3 min, whereas the in vivo studies also reported that the extract could successfully increase the GLP-1 levels compared with the control group