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Many individuals taking tirzepatide report substantial reductions in caloric intake, which, while beneficial for weight loss, creates potential challenges for maintaining adequate protein consumptiona critical macronutrient for preserving lean muscle mass during weight reduction

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These SMILES were then used as input for the tools SuperPred 59 and SwissTargetPrediction (STP) 60 to identify potential protein targets of the drugs

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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease