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Nanoparticles were designed with a 2,2-(propane-2,2-diylbis(sulfanediyl)) bis(ethan-1-ol) linker that could be oxidized by ROS, decompose into oligomeric units, and release the ruthenium catalyst

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NAD supports the enzymatic reactions that convert harmful compounds into forms that can be eliminated

Benowitz 2024)

Once mutant and/or misfolded proteins with a loss- or gain-of-function or damaged and potentially harmful cellular structures cannot be effectively eliminated, cells undergo malignant transformation, which may progress to carcinogenesis (Edinger and Thompson, 2017) (Figure 2)