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TriNetX has been widely used for real-world evidence studies across multiple medical disciplines and supports pharmacoepidemiologic analyses using methods such as propensity score matching and time-to-event modelling ( Study design and target trial emulation We designed this study to emulate a hypothetical target trial ( Supplementary Table 1 )

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In addition to modulation in appetite and food intake, body weight reduction from caloric restriction causes a decrease in energy expenditure beyond what is predicted by the change in body mass

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10.1007/s11883-017-0678-6 Curr Atheroscler Rep