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Oral treatment reduced proliferation and TNF- generation in mice, and EGCG prevented TRAIL-induced neuronal injury in living brain tissue [125]

This effectively reduces the number of immunosuppressive cells and enhances the anti-tumor ability and long-term memory immunity of CAR-T cells

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Finally, GLP-1 receptor agonists may improve lung function by reducing body weight, as abdominal obesity decreases lung capacity by pushing the diaphragm into the chest cavity

How well lean muscle can be preserved at this magnitude of weight loss is an active research question