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It is possible that combination therapy offers advantages over monotherapy, opening the debate on whether it should always be adopted as first-line treatment, reserved only for a brief initial phase followed by maintenance monotherapy, or applied only in patients who do not respond to monotherapy

Consult your physician before starting any new medication

The effect isn't a matter of willpower

However, certain red-flag symptoms warrant immediate contact with your provider: a lump that grows larger after 48 hours, increased redness or warmth spreading beyond the injection site, pus or drainage, fever, or severe pain that interferes with daily function

Consuming food or extra liquid too soon can block the absorption of the drug, rendering the dose ineffective

[17] The mechanism of action involves binding to cytosolic glucocorticoid receptors, which are present in virtually all human tissues and cell types