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Although there are no clear doseeffect data, a threshold exists for the development of alcoholic hepatitis, with risk increasing with consumption beyond 40 g of alcohol per day

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& Griffin, J

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[7] The protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell death and increases resistance to toxic challenges, especially oxidative stress