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PCR showed that Exendin-4 down-regulated the expression of senescence associated gene (p16, p21, p53) and up-regulated the expression of bone-related gene

doi: 10.1038/labinvest.2016.76 134 BeachTAGrovesAMWilliamsJPFinkelsteinJN

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These medications have been shown to lead to significantly lower self-reported hunger, reduced food intake, and increased awareness around hunger cues and eating in response to environmental or emotional triggers

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