Jorgensen, R., Martini, L., Schwartz, T
Part 2 Insurance companies: Fixed margin Want costs to rise predictably and steadily, not by surprise In support of GLP1s over time, not immediately, so they can be priced in PBMs: Benefit from higher priced drugs with rebates Pharmacies: Benefit from volume of prescriptions Benefit from foot traffic from prescriptions Pharma: Benefit from blockbuster drugs Summary of existing players: four key stakeholders benefit from higher priced blockbusters drugs over a long-term time horizon under most circumstances
Now, Enter GLP-1 Receptor Agonists GLP-1 receptor agonists act centrally and peripherally
Similarly, GLP-1RA have shown to have a neuroprotective effect including delay in Alzheimers and Parkinsons disease onset as well progressions (118)
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Pasteurized (heat-killed) forms have shown benefits in human trials, and products like the Pendulum GLP-1 Probiotic use proprietary encapsulation to deliver viable organisms