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The GST activity (A), ALDH activity (B) and TBARS (C) levels of the liver tissues 5 hours after the treatment were examined (n = 10)

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Transgenic lines expressing roGFP2 indicated a change in the glutathione redox potential upon AITC treatment The application of AITC led to stronger responses for the glutathione mutants than for WT, which may suggest an essential role for this tripeptide in the AITC-induced physiological responses

For instance, Tao et al

2-Methylbutyryl-CoA can also be converted to its carnitine derivative, 2-methylbutrylcarnitine (2MBC) via the action of carnitine O -acetyltransferase encoded by the CRAT gene

The buildup of misfolded or damaged proteins, such as amyloid- in AD and -synuclein in PD, occurs due to the failure of these pathways, causing cellular stress, inflammation, and neurodegeneration