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Epub 2014 Jun 27

The increases peaked around week 24 and then declined

Luckily, both B12 injections and oral supplements are able to help regulate this deficiency

Stay on top of your B12 levels and explore ways to maintain overall well-being

Proposed Mechanisms Preventing GABA receptor downregulation Counteracting compensatory NMDA glutamate receptor sensitization Stabilizing benzodiazepine receptor configuration (preventing shift to inverse agonist state) Upregulating GABAergic neurotransmission through pathways distinct from benzodiazepine action itself This tolerance prevention has profound clinical implications

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