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We additionally summarize the evidence by domain and certainty level in a structured Supplementary Table 6, explicitly separating relatively robust short-term metabolic evidence from more exploratory reproductive and periconception safety findings

Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model

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Dopamine is critical for motor control, and its deficiency in PD impairs the basal ganglia's ability to coordinate smooth, voluntary movements

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