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Fierro B, Giglia G, Palermo A, Pecoraro C, Scalia S, Brighina F

& Kissen, R

10 th ed

Potential Benefits Antidepressant-like (preclinical): Rodent behavioural models report rapid antidepressant-like effects after TREK-1 blockade [3] [4]

Subjects with known clinically relevant comorbidity, acute illness, serious infectious disease for 4 weeks prior the product intake, abnormal screening laboratory tests, and abnormal blood pressure (systolic blood pressure 139 mmHg and/or diastolic blood pressure 89 mmHg) were excluded, although subjects with normal blood pressure taking anti-hypertensive medication were included

TB-500 is studied for its influence on actin a structural protein essential for cell movement and wound healing and for its support of new blood-vessel formation (angiogenesis)