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The European Medicines Agency recommends careful monitoring and avoiding high doses to prevent severe side effects and ensure patient safety

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Chronic inflammation leads to dysfunction of the endometrium by influencing the proliferation and apoptosis of endometrial cells, thereby increasing the risks of endometrial hyperplasia, PCOS, and cancer ( 3.7 Gut microbiota The gut microbiota, often referred to as the human bodys second genome ( Additionally, PCOS is associated with an increased abundance of Gram-negative bacteria ( e.g ., Enterobacteriaceae), which produce lipopolysaccharide (LPS)
10.5511/plantbiotechnology.18.0205a 169 WallerF.AchatzB.BaltruschatH.FodorJ.BeckerK.FischerM.et al