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2021 Jun:167:37-43

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Raghu G, Berk M, Campochiaro PA, Jaeschke H, Marenzi G, Richeldi L, Wen FQ, Nicoletti F, Calverley PMA

Its capacity to induce apoptosis in cancer cells is attributed to the activation of the AMPK pathway

Derived from fungi (particularly Aspergillus oryzae , used in sake and miso production), kojic acid is one of the most effective natural tyrosinase inhibitors available in cosmetic formulations

Functional studies revealed that GPX4 knockdown suppresses the proliferation and colony formation of NPC cells