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the macules may be present on the shaft of the penis or on the glans penis The presence of numerous melanotic macules on the body may be associated with a variety of syndromes including Carney complex, Peutz-Jeghers syndrome, and LEOPARD syndrome

Key considerations include: Patient Access and Equity: Limited coverage under pharmacy benefits means many patients (especially obese patients without diabetes) lack access to effective treatment

The drug primarily affects glucose metabolism, appetite regulation, and gastric motility rather than adrenal hormone synthesis

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In patients diagnosed with hypertriglyceridaemia, secondary causes should be first ruled out, as appropriate management of a concomitant condition or modification of medications used may improve lipid profile