Although chronic periodontitis patients exhibit higher gastric H
They, and then GLP ones, remember I said they lower systemic inflammatory burden
Under oxidative stress, NRF2 was released from KEAP1, translocated into and accumulated in the nucleus to induce expression of its target genes, and increased the expression of antioxidant enzymes like SODs and HOs families 60
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Notably, among patients with T2DM and liver biopsy data (n = 12 studies involving 2,733 patients), the global pooled prevalence of MASH, significant fibrosis, and advanced fibrosis was 66.4 %, 40.8 %, and 15.5 %, respectively (Younossi et al., 2024[87])
Naunyn-Schmiedeberg's Arch Pharmacol 396 , 13611370 (2023)