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They have supplemented this formulation to male participants of a clinical trial of this drug for 2 to 5 months at a daily dose of 2 capsules before their semen has taken for IVF and intra-cytoplasmic sperm injection (ICSI)

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Section symposium, Honolulu, Hawaii, 13:032 Veljaca M, Sladoljev P, Mildner B (2003) Tolerability and pharmacokinetics of PL 14736, a novel agent for treatment of ulcerative colitis, in healthy male volunteers