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Chapter 1: A GLP-1 Contrarian Play Amylyx is taking the opposite approach to the GLP-1 boom: instead of developing agonists for weight loss, the company is developing a GLP-1 antagonist

How does semaglutide and other drugs of its type manage diabetes on a molecular level, and what drives the weight loss effects

These observations have long encouraged the notion that AngIV-based pharmaceuticals may have potential as antidementia therapeutics (Mustafa et al., 2001