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FDA approval projected late 2027

That 300mg dose puts users in a good spot to titrate, similar to the 250mg NMN dose from Neurogan Health

30 ChenD.ZhengQ.SunL.JiM.LiY.DengH.et al (2021)

Within the cardiovascular system, L-citrulline enhances NO bioavailability by promoting the phosphorylation and activation of endothelial NO synthase (eNOS), thereby improving endothelial function ( Figure 2b ) ( Figure 2c ) ( L-citrullines regulatory influence further extends to immune and metabolic systems