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doi: 10.3389/fnut.2023.1134162 Received 30 December 2022 Accepted 22 June 2023 Published 20 July 2023 Volume 10 - 2023 Edited by Xiaoping Yang, Hunan Normal University, China Reviewed by Lorenzo Lorusso, ASST Lecco, Italy

36 Month Systemic Protocol CJC-1295/Ipamorelin is administered via subcutaneous injection, typically 5 nights per week before sleep (to align with the body's natural nocturnal GH pulse)

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In 2019, an oral formulation of semaglutide became the first orally administered GLP-1RA to be approved [3, 24]