The effects of this presentation on weight and glycemia in clinical trials and real-world settings are comparable to those induced by the subcutaneous presentation, although a specific indication for weight control without DT2 is still lacking.86 In order to avoid confusion in daily clinical practice, it is important to note that liraglutide 3mg and semaglutide 2.4mg can be used in patients with DT2, provided these are obese or overweight with comorbidities
With GLP-1s shrinking appetite, there are even fewer opportunities to hit that goal making fiber an even higher priority
Patients running both compounds often see C-reactive protein drop within 8 to 10 weeks, which is faster than either peptide produces alone in my experience
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In some cases, doctors may still prescribe them off-label (for other uses that are not FDA-approved), depending on individual needs and their own medical judgement
