Focus on: High-protein foods (lean meat, fish, eggs, legumes, Greek yoghurt) at each meal to enhance satiety High-fibre vegetables and whole grains to slow digestion and prolong fullness Adequate hydration (6-8 glasses of fluid daily, approximately 1.2 litres, more during hot weather or exercise), as thirst is often mistaken for hunger Regular meal timing (three balanced meals with planned snacks if needed) to stabilise blood glucose and prevent extreme hunger Minimising ultra-processed foods and refined sugars that cause rapid blood glucose fluctuations Addressing lifestyle factors can significantly improve appetite regulation
This potential antidepressant effect of semaglutide is attributed to being a GLP-1R agonist causing stimulation of adenylyl cyclase and consequently cAMP
Variety nourishes different beneficial gut bacteria
Weight loss on GLP-1s can help some patients meet BMI thresholds for IVF and reduce anesthesia risk, although larger studies are still needed to prove a direct improvement in egg quality or live birth rates
The right choice depends on your health profile, your weight loss goals, your budget, and your tolerance for newer versus more established treatments
Heres some general safety information about these medications: GLP-1s carry a boxed warning about thyroid C-cell tumors occurring in rodents (with unknown risk in humans)