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This release of secondary messenger molecules such as IP3 might potentially stimulate the discharge of calcium ions (Ca2+) from the cell's internal stores, while DAG might activate protein kinase C (PKC)

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Exposure Health 11(4):267275 Ali S, Fakhri Y, Golbini M, Thakur S, Alinejad A, Parseh I, Shekhar S, Bhattacharya P (2019) Concentration of fluoride in groundwater of India: a systematic review, meta-analysis and risk assessment