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At DripGym, nurses are trained to modulate the infusion rate in real time based on patient feedback, typically extending higher-dose infusions over 3-4 hours rather than rushing them

Furthermore, they are easy to transport, and discreet which makes it easier for subjects of clinical research to incorporate them into their daily routines

Notably, animal models have demonstrated that transferring dysbiotic microbiota from CFS/ME patients to germ-free mice can induce fatigue-like behaviors, supporting a causal role for the microbiome in disease pathogenesis ( 3.5.4 Gut microbiota-based therapeutic interventions 3.5.4.1 Probiotics Given these findings, probiotic supplementation, particularly with strains of Lactobacillus and Bifidobacterium , has shown potential to restore microbial balance, enhance SCFA production, and reduce inflammation in CFS/ME patients (Skjevling et al., 2024)

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Blood oxygen level-dependent (BOLD) MRI provides an indirect measure of tissue oxygenation by detecting variations in deoxyhaemoglobin concentration (187189), making it a useful surrogate marker for tumour hypoxia