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As a result, it does not produce insulin and diabetes will be created (35)

We propose that the increase in circulating glucagon observed following genetic/pharmacological inactivation of glucagon signalling in mice and in people with type 2 diabetes reflects the removal of GLP-1(936)s glucagonostatic action

Hayashi Y, Ajani JA, Correa A, Hofstetter WL, Vaporciyan AA, Rice DC, Walsh GL, Mehran RJ, Suzuki A, Lee JH, Bhutgani M, Lin SH, Welsh J, Maru DM, Swisher SG

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