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It is noteworthy that initial urine osmolarity findings, despite not being immediate, indicated no significant differences between the groups

Scotto Rosato A, Montefusco S, Soldati C, Di Paola S, Capuozzo A, Monfregola J et al (2019) TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKK/VPS34 pathway

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Do not re-treat animals for 8 weeks after the last treatment

10.2174/1570159X19666201215142520 87 RathourD.ShahS.KhanS.SinghP

Interestingly, opiate withdrawal appeared more resistant to intervention, requiring multiple DSIP administrations over an extended period for observable effects