Metabolic Research Glucose Homeostasis & Insulin Secretion (NIH/PubMed) Bhavsar, S
Months 6 through 12 usually see continued but slower weight loss as the body approaches a new equilibrium
Many individuals begin experiencing reduced hunger, improved portion control, and fewer cravings as their body adjusts to the treatment
(abstract) (webcast) Lake J E et al
Lift Heavy 2 to 3 Days Per Week The Longland 2016 trial (n=40, 4 weeks, ~40% deficit) showed that the high-protein arm at 2.4 g/kg/day actually GAINED 1.2 kg of lean mass while losing 4.8 kg of fat, and the lower-protein arm at 1.2 g/kg/day held lean mass roughly flat while losing 3.5 kg of fat [4]
Research shows that weight regain after discontinuing semaglutide is common, often occurring within three to six months