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Results at Week 56 in a Trial of OZEMPIC Compared to Sitagliptin in Adult Patients with Type 2 Diabetes Mellitus in Combination with Metformin and/or Thiazolidinediones aThe intent-to-treat population includes all randomized and exposed patients

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Glutathione (GSH) is a tripeptide molecule made from three amino acids: Cysteine (rate-limiting amino acid-contains sulfur) Glycine Glutamate It exists in two forms: Reduced glutathione (GSH) : Active form, the antioxidant Oxidized glutathione (GSSG) : Inactive form, created when GSH neutralizes free radicals The GSH:GSSG ratio is a critical marker of oxidative stress

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The SURMOUNT-1 Phase 3 trial published in The New England Journal of Medicine enrolled 2,539 adults with obesity and demonstrated mean body weight reduction of 20.9% at 72 weeks on tirzepatide 15mg weekly versus 3.1% placebo

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