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These medications may be prescribed to eligible individuals and can complement care for certain health conditions

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x Stronger appetite control than other options

Dose escalation should follow clinical guidance and occur incrementally every 4 weeks

The FDA has also flagged BPC-157 as a bulk drug substance that may present significant safety risks when used in compounding, noting limited safety information and concerns like immunogenicity for certain routes of administration and peptide-related impurities

In this trial, 3,183 adult patients with inadequately controlled type 2 diabetes mellitus and atherosclerotic CV disease were randomized to Rybelsus 14 mg once daily or placebo for a median observation time of 16 months