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To induce PCOS, the rats were administered dehydroepiandrosterone (DHEA) (Sigma, 6 mg/100 g body weight dissolved in 0.2 ml sesame oil) via subcutaneous injection for 21 consecutive days 24,53,54

Significant appetite suppression and reduced food intake should be managed with a balanced diet containing adequate protein per NHS guidance

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Table 1 summarizes the evidence of the use of selenium in different thyroid disease etiologies and their results