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Regular contact reduces the risk of silent medication issues and enables rapid dose adjustment or discontinuation if needed

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Common short-term side effects include gastrointestinal discomfort that typically improves with dose titration, while longer-term safety monitoring focuses on metabolic markers, gallbladder disease signals, and rare adverse events identified in post-marketing surveillance

In summary, the hGPR17L-mediated calcium mobilization in GLUTag cells appears to be dependent on both Gi/o- and Gq signaling

doi: 10.1016/j.cell.2019.08.031 56 SullivanJMBoreckiAAOleskevichS