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Lillig et al., 2008)

Regulation of 2-AR on ICC cell proliferation and signaling pathway -ARs play an important role in ICC, primarily by regulating cell proliferation and the MAPK signaling pathway

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Altogether, these animal and human studies show that intermittent fasting either during daily activity or inactivity hours (with or without extending to activity hours) have an anticancer effect compared with ad libitum eating