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Additionally, excluding patients with a diagnosis of any psychiatric diseases within one year before or one month after the index date may not be sufficient to avoid bias
Such serum inevitably contains a mixture of antibodies which means the antibodies will vary in their specificity
However, newer GLP-1 medications, such as tirzepatide, which target both GLP-1 and GIP receptors, may be even more effective for weight loss
In clinical practice, it was also found that immune activation led to a rapid and significant upregulation of GLP-1R expression in naive CD4 + T cells enriched more than 40-fold from the human body (93)
The growing approval pipeline could have significant implications for driving future improvements in morbidity and mortality, beyond areas discussed in Part 2
But the laboratory data is clear, and it aligns with the clinical observations of patients who report improvement when adding GLP-1 medications to their existing treatment regimens
