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The most common concern is increased gastrointestinal symptoms, particularly nausea, as both medications can cause digestive upset

In addition, it is remarkable that the genes required for self-protection against the noxious effects of DTG and/or gliotoxin (i.e., gliA , gliT , and gtmA ) (Vicentefranqueira et al., 2018)

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Plasma AUC levels of sitagliptin were increased approximately 2-fold and 4-fold in patients with moderate renal insufficiency and in patients with severe renal insufficiency, including patients with ESRD on hemodialysis, respectively

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doi: 10.1152/ajpheart.1981.241.3.H415 191 SheltonELWalehNPlosaEJBenjaminJTMilneGLHooperCWet al