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its dual-hormone action affects digestion more strongly

doi: 10.1038/s41467-023-38097-1

Their primary mechanisms include: Enhancing insulin secretion from pancreatic beta cells in response to elevated blood glucose Suppressing glucagon release , thereby reducing hepatic glucose production Slowing gastric emptying , which prolongs satiety and reduces appetite Acting on appetite centres in the brain , particularly the hypothalamus, to reduce food intake [17] [18] These combined effects lead to improved glycaemic control in people with type 2 diabetes and significant weight reduction in those using these medications for obesity management

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A 2003 study published in the Journal of Medicinal Food found that chrysin may help to improve testosterone levels in men ( 53 )

in the STEP-1 trial it produced about 14.9% mean weight loss over 68 weeks ( Wilding et al., NEJM 2021 )