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Randomized, placebo-controlled, double blind study on the clinical efcacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin

Hudson (OH): Lexicomp, Inc

The United Kingdom Prospective Diabetes Study (UKPDS) 80 reported that intensive treatment of hyperglycemia considerably reduced the risk of myocardial infarction and death in patients with early diagnosed T2DM followed up during a 10-year post-trial period [3]

And there are concerns that patients regain weight quickly if and when they stop taking the drug

In addition, patients with PWS have a higher incidence of metabolic complications, such as CVD, T2D, hypertension, and obstructive sleep apnea [5, 14, 15], thus contributing to increased morbidity and mortality in these patients [14, 16]