Dornier, E., Rabas, N., Mitchell, L., Novo, D., Dhayade, S., Marco, S
Following rigorous quality control measures, which included the exclusion of duplicate entries, reports with incomplete demographic data (age or gender), and cases with missing temporal information, we retained 13,047 AE reports associated with concomitant GLP-1 receptor agonist and metformin therapy for final analysis
Asimakopoulou et al
Patient Hope Patients waiting for retatrutide are a combination of hopeful and cautious
As an obesity medicine physician scientist who regularly cares for patients with complex inflammatory conditions, this study reinforces what many of us have suspected clinicallythat the benefits of GLP-1 receptor agonists extend well beyond blood sugar control and weight loss and may fundamentally alter the disease trajectory for some of our highest-risk patients. Although this study cannot prove a causal link between GLP-1 medication and the effects seen on the patients taking them, it opens the door to future combinations of treatments for autoimmune disease with GLP-1 drugs
Oct 2010;95(10):4743-4747