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( Astragalus mongholicus Bunge (Leguminosae) and Panax notoginseng (Burkill) F.H.Chen (Araliaceae) formulation in combination with Bifidobacterium was found to protect kidneys in CKD by decreasing macrophage inflammatory response in the kidney and intestine via inhibiting Mincle signaling ( In the practice of TCM, a large number of Yang/Qi-invigorating tonic formulations have been shown to alleviate CKD-related symptoms, such as proteinuria, edema, and decreased glomerulus filtration

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